Many thanks for all your work on this and persistence, we got there in the end!
Ms C. Owen
Encouraging Research Into The Cause of Unwanted Side Effects of Morphine
Wed 4th Apr 2012 Clinical negligence
Research scientists in the USA have discovered a receptor in the brain which may hold the key to why there are so many unwanted side effects of Morphine.
Morphine is an opiate-based pain killer used extensively around the world to manage moderate to
severe symptoms of pain associated with conditions such as cancer, arthritis and
acute trauma to name but a few. Unfortunately,
although an effective pain killer, there are many undesirable side effects
associated with Morphine, which in turn often require further drug treatments.
Side effects include: constipation, allergy, itching, confusion, nausea and
respiratory depression. In addition, over time with prolonged use patients can
become resistant to Morphine and develop an increased sensitivity to pain.
Previously it has been thought that these inflammatory side effects were triggered by the opiate-receptors in the body, however scientists have discovered that Opiates like Morphine can create an inflammatory response through the activation of an immune receptor in the brain. Furthermore, they have demonstrated how this immune receptor in the brain can be blocked, which could, in time, potentially lead to the development of new therapeutic drugs that improve the effectiveness of morphine while reducing many of its problematic side effects.
Read more here.
Nurse Adviser and Medical Researcher - Clinical Negligence team
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