this article on BBC News Health, that around 32,000 people in the UK die after developing a blood clot. I tend to associate these with a deep view thrombosis (DVT) for example after a long haul flight. I did not appreciate that having high cholesterol increased your risk.

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Cholesterol Drugs Could Cut Blood Clots

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I was surprised to read this article on BBC News Health, that around 32,000 people in the UK die after developing a blood clot. I tend to associate these with a deep view thrombosis (DVT) for example after a long haul flight. I did not appreciate that having high cholesterol increased your risk.

The team at the University of Reading was investigating how clots form and say they were surprised to find that protein, LXR, was involved. LXR is already known to control levels of cholesterol and drug companies have been targeting it for new treatments.

Researchers, writing in the journal Blood, reduced the size and stability of blood clots in mice and said the discovery could lead to new drugs.

The British Heart Foundation said it was an exciting discovery which could result in more effective treatments.

Professor Jeremy Pearson, associate medical director at the British Heart Foundation, said: "Both anti-clotting and cholesterol lowering drugs are vital in reducing the chance of a heart attack or stroke in high-risk patients, but are not always effective and don't suit all patients because of the risk of side-effects.

"This exciting discovery shows that drugs which lower cholesterol through targeting LXR protein can also reduce harmful blood clotting - potentially opening up paths towards new, more effective treatments."

I say that this is excellent news for those with high cholesterol. It is great to hear how much research is being done in this area.

Patricia Wakeford

Solicitor - Clinical Negligence team


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